{"id":2455,"date":"2022-11-17T11:12:38","date_gmt":"2022-11-17T02:12:38","guid":{"rendered":"http:\/\/simagebank.godohosting.com\/wp\/?p=2455"},"modified":"2022-11-17T14:05:14","modified_gmt":"2022-11-17T05:05:14","slug":"%ec%84%b8%ed%8f%ac%eb%a7%89-%ec%8b%a0%ed%98%b8%ec%a0%84%eb%8b%ac","status":"publish","type":"post","link":"https:\/\/simagebank.net\/wp\/2455\/","title":{"rendered":"\uc138\ud3ec\ub9c9 \uc2e0\ud638\uc804\ub2ec"},"content":{"rendered":"\n

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(<\/strong>\uac00<\/strong>) <\/strong>\uc138\ud3ec\ub9c9\uc740 \ub300\ubd80\ubd84\uc758 \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec\uc5d0\uc11c \ud575\uc2ec\uc801 \uc5ed\ud560\uc744 \ub2f4\ub2f9\ud55c\ub2e4<\/strong>.<\/strong><\/p>\n\n\n\n

<\/strong>\uadfc\uac70\ub9ac \ubc0f \uc6d0\uac70\ub9ac \uc2e0\ud638 \uc804\ub2ec<\/strong>: \uc138\ud3ec \uc0ac\uc774\uc5d0\uc11c \ud654\ud559\uc2e0\ud638\ub294 \uc9c1\uc811\uc801\uc778 \uc138\ud3ec\uc9c8\uc758 \uc5f0\uacb0(\uac04\uadf9\uc5f0\uc811 \ub610\ub294 \uc6d0\ud615\uc9c8 \uc5f0\ub77d\uc0ac)\uc774\ub098 \ub9c9 \ud45c\uba74 \ubd84\uc790\uc758 \uc811\ucd09\uc73c\ub85c \uad50\ud658\ub420 \uc218 \uc788\ub2e4.<\/p>\n\n\n\n

\ub3d9\ubb3c\uc758 \uadfc\uac70\ub9ac \uc2e0\ud638 \uc804\ub2ec\uc5d0\uc11c\ub294 \uc2e0\ud638 \uc138\ud3ec\uac00 \uc2e0\ud638 \ubd84\uc790\ub4e4\uc744 \uc138\ud3ec\uc678\uc6a9\uc561\uc73c\ub85c \ubd84\ube44\ud558\uace0, \uc774 \uad6d\uc18c \uc870\uc808\uc790(local regulator)\ub4e4\uc774 \uac00\uae4c\uc774\uc5d0 \uc788\ub294 \uc138\ud3ec\uc5d0 \uc601\ud5a5\uc744 \uc900\ub2e4. \uc0dd\uc7a5 \uc778\uc790 (growth factors)\ub294 \uc774\ub7ec\ud55c \uad6d\uc18c \uc870\uc808\uc790\uc758 \ud55c \uc885\ub958\uc774\ub2e4. \uc2dc\ub0c5\uc2a4 \uc804\ub2ec(synaptic signaling)\uc774\ub77c \ubd88\ub9ac\ub294 \ub2e4\ub978 \uc885\ub958\uc758 \uad6d\uc18c\uc870\uc808\uc5d0\uc11c\ub294 \uc2e0\uacbd\uc138\ud3ec\uac00 \uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8\uc744 \ubd84\ube44\ud558\uba74, \uc774\uac83\uc774 \uc881\uc740 \uc2dc\ub0c5\uc2a4\ub97c \ub530\ub77c \ud655\uc0b0\ud558\uc5ec \ud45c\uc801 \uc138\ud3ec\uc5d0 \ub3c4\ub2ec\ud55c\ub2e4.<\/p>\n\n\n\n

\ud638\ub974\ubaac(hormone)\uc740 \ub354 \uba40\ub9ac\uc5d0 \uc788\ub294 \uc138\ud3ec\ub85c \uc804\ub2ec\ub418\ub294 \ud654\ud559\uc2e0\ud638\uc774\ub2e4. \ub3d9\ubb3c\uc758 \ud638\ub974\ubaac \ub610\ub294 \ub0b4\ubd84\ube44 \uc2e0\ud638(endocrine signaling)\uc5d0\uc11c\ub294 \ud638\ub974\ubaac\uc774 \uc21c\ud658\uacc4\uc5d0 \uc758\ud574 \ubab8\uc758 \uad6c\uc11d\uad6c\uc11d\uc73c\ub85c \uc6b4\ubc18\ub418\uc5b4 \uc801\uc808\ud55c \uc218\uc6a9\uccb4\ub97c \uac00\uc9c4 \ud45c\uc801 \uc138\ud3ec\uc5d0 \uacb0\ud569\ud55c\ub2e4. \uc2dd\ubb3c \ud638\ub974\ubaac\uc740 \uad00\ub2e4\ubc1c\uc870\uc9c1\uc744 \ud1b5\ud574\uc11c \ub610\ub294 \uac00\uc2a4\ub85c\uc11c \uacf5\uae30\ub97c \ud1b5\ud574\uc11c \ud45c\uc801 \uc138\ud3ec\uc5d0 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub2e4.<\/p>\n\n\n\n

\uc2e0\uacbd\uacc4 \ub0b4\uc5d0\uc11c \uc804\uae30\uc801 \ub610\ub294 \ud654\ud559\uc801 \uc2e0\ud638\uc758 \uc804\ub2ec \ub610\ud55c \uc6d0\uac70\ub9ac \uc2e0\ud638 \uc804\ub2ec\uc758 \ud55c \uc885\ub958\uc774\ub2e4.<\/p>\n\n\n\n

<\/strong>\uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec\uc758 \uc138 \ub2e8\uacc4<\/strong> : \uac04\uc5d0\uc11c\uc758 \uae00\ub9ac\ucf54\uac90 \uac00\uc218\ubd84\ud574\uc5d0 \ubbf8\uce58\ub294 \uc5d0\ud53c\ub124\ud504\ub9b0\uc758 \uc601\ud5a5\uc5d0 \uad00\ud55c \uc11c\ub354\ub79c\ub4dc\uc758 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec\uc774 \ud45c\uc801 \uc138\ud3ec\uc758 \ud45c\uba74 \ub610\ub294 \ub0b4\ubd80\uc5d0 \uc704\uce58\ud558\ub294 \uc218\uc6a9\uccb4 \ub2e8\ubc31\uc9c8\uacfc\uc758 \uacb0\ud569\uc5d0 \uc758\ud55c \ud654\ud559\uc2e0\ud638\uc758 \uc218\uc6a9<\/strong>(reception), \uc8fc\ub85c \uc911\uacc4\ubd84\uc790\uac00 \uc5f0\uc18d\uc801\uc73c\ub85c \ubcc0\ud654\ud558\ub294 \uc2e0\ud638\uc804\ub2ec\uacbd\ub85c<\/strong>(signal transduction pathway)\ub97c \uac70\uce58\ub294 \uc2e0\ud638\uc758 \uc804\ud658<\/strong>(transduction), \uc138\ud3ec\uc758 \ud2b9\uc815\ud55c \ubc18\uc751<\/strong>(response)\uc758 \uc138 \ub2e8\uacc4\ub85c \uc77c\uc5b4\ub09c\ub2e4\ub294 \uac83\uc744 \uc54c\uac8c \ub418\uc5c8\ub2e4.<\/p>\n\n\n\n

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(\ub098) \uc2e0\ud638 \ubd84\uc790\uac00 \uc218\uc6a9\uccb4 \ub2e8\ubc31\uc9c8\uc5d0 \uacb0\ud569<\/strong><\/p>\n\n\n\n

\uc2e0\ud638 \ubd84\uc790\ub294 \ub9ac\uac04\ub4dc(ligand)\ub85c\uc368 \uc791\uc6a9\ud558\uc5ec \uc218\uc6a9\uccb4 \ub2e8\ubc31\uc9c8\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \uc218\uc6a9\uccb4\uc758 \uad6c\uc870\uc5d0 \ubcc0\ud654\ub97c \uc720\ubc1c\ud558\uc5ec \uc218\uc6a9\uccb4\ub97c \ud65c\uc131\ud654\ud55c\ub2e4. \ub300\ubd80\ubd84\uc758 \ub9ac\uac04\ub4dc\ub294 \ud06c\uace0 \uc218\uc6a9\uc131\uc774\uba70, \uc138\ud3ec\ub9c9\uc5d0 \uc788\ub294 \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud55c\ub2e4.<\/p>\n\n\n\n

G \ub2e8\ubc31\uc9c8\uc758 \ub3c4\uc6c0\uc73c\ub85c \uc791\ub3d9\ud558\ub294 \uc138\ud3ec \ud45c\uba74\uc758 \ub9c9\uad00\ud1b5 \uc218\uc6a9\uccb4\ub294 G \ub2e8\ubc31\uc9c8 \uacb0\ud569 \uc218\uc6a9\uccb4(G protein-coupled receptor, GPCR)\ub77c \ubd88\ub9b0\ub2e4. \uc801\uc808\ud55c \uc2e0\ud638 \ubd84\uc790\uac00 G \ub2e8\ubc31\uc9c8 \uacb0\ud569 \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud558\uba74 \uc218\uc6a9\uccb4\uac00 \ud65c\uc131\ud654\ub418\uace0, \uc138\ud3ec\ub9c9\uc758 \uc138\ud3ec\uc9c8 \ucabd \ud45c\uba74\uc5d0 \uc704\uce58\ud558\ub294 \ud2b9\uc815\ud55c G \ub2e8\ubc31\uc9c8\uc5d0 \uacb0\ud569\ud558\uc5ec \uc774\ub97c \ud65c\uc131\ud654\ud55c\ub2e4. \ud65c\uc131\ud654\ub41c G \ub2e8\ubc31\uc9c8\uc740 GTP \ubd84\uc790\ub97c \uac00\uc9c0\uace0 \uc788\ub294\ub370, \ub9c9\uc5d0 \uacb0\ud569\ud574 \uc788\ub294 \ud6a8\uc18c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \uacbd\ub85c\uc758 \ub2e4\uc74c \ub2e8\uacc4\ub97c \uc720\ubc1c\ud558\uace0 \uc138\ud3ec \ubc18\uc751\uc744 \uc77c\uc73c\ud0a8\ub2e4.<\/p>\n\n\n\n

G \ub2e8\ubc31\uc9c8 \uacb0\ud569 \uc218\uc6a9\uccb4 \uc2dc\uc2a4\ud15c\uc740 \uc5ec\ub7ec \ud638\ub974\ubaac\uacfc \uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8\uc758 \uae30\ub2a5\uacfc \ubc30\uc544\uc758 \ubc1c\uc0dd \ubc0f \uac10\uac01\uc218\uc6a9 \ub4f1\uacfc \uad00\ub828\ub418\uc5b4 \uc788\ub2e4. \ub9ce\uc740 \uc138\uade0\uc740 G \ub2e8\ubc31\uc9c8\uc758 \uae30\ub2a5\uc744 \uc800\ud574\ud558\ub294 \ub3c5\uc18c\ub97c \ub9cc\ub4dc\ub294\ub370, \ubaa8\ub4e0 \uc57d\ubb3c\uc758 \uc57d 60%\uac00\ub7c9\uc774 G \ub2e8\ubc31\uc9c8 \uacbd\ub85c\uc640 \uad00\ub828\uc131\uc774 \uc788\ub2e4.<\/p>\n\n\n\n

\uc2e0\ud638 \ubd84\uc790\ub294 \ub9ac\uac04\ub4dc \uac1c\ud3d0\uc131 \uc774\uc628 \ud1b5\ub85c(ligand-gated ionchannel)\uc5d0 \uacb0\ud569\ud558\uc5ec \uad00\ubb38\uc744 \uc5f4\uac70\ub098 \ub2eb\uc74c\uc73c\ub85c\uc368 \uc218\uc6a9\uccb4 \ud1b5\ub85c\ub97c \ud1b5\ud55c \ud2b9\uc815\ud55c \uc774\uc628\uc758 \ud750\ub984\uc744 \ud5c8\uc6a9\ud558\uac70\ub098 \ub9c9\uc744 \uc218 \uc788\ub2e4. \uadf8 \uacb0\uacfc \ub098\ud0c0\ub098\ub294 \uc138\ud3ec \ub0b4 \uc774\uc628 \ub18d\ub3c4\uc758 \ubcc0\ud654\ub294 \uc138\ud3ec \ubc18\uc751\uc744 \uc720\ubc1c\ud55c\ub2e4. \uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8\uc740 \ub300\uac1c \ub9ac\uac04\ub4dc \uac1c\ud3d0\uc131 \uc774\uc628 \ud1b5\ub85c\uc5d0 \uacb0\ud569\ud558\uc5ec \uc2e0\uacbd \uc2e0\ud638\ub97c \uc804\ub2ec\ud55c\ub2e4.<\/p>\n\n\n\n

\uc18c\uc218\uc131 \ud654\ud559 \uc804\ub2ec\uc790\uc640 \uac00\uc2a4\uc778 \uc0b0\ud654\uc9c8\uc18c\uc640 \uac19\uc740 \uc791\uc740 \uc2e0\ud638 \ubd84\uc790\ub294 \uc138\ud3ec\ub9c9\uc744 \ud1b5\uacfc\ud560 \uc218 \uc788\uc5b4 \ud45c\uc801 \uc138\ud3ec\uc758 \uc138\ud3ec\uc9c8\uc774\ub098 \ud575\uc5d0 \uc788\ub294 \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud55c\ub2e4. \uc2a4\ud14c\ub85c\uc774\ub4dc \ud638\ub974\ubaac\uc740 \ud45c\uc801 \uc138\ud3ec\uc758 \uc218\uc6a9\uccb4\ub97c \uc804\uc0ac\uc778\uc790\ub85c \uae30\ub2a5\ud558\ub3c4\ub85d \ud65c\uc131\ud654\ud558\uc5ec \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud55c\ub2e4.<\/p>\n\n\n\n

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\ucc38\uace0\uc790\ub8cc: \ucea0\ubca8 \uc0dd\uba85\uacfc\ud559 \uc694\uc57d<\/p>\n\n\n\n

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(\uac00) \uc138\ud3ec\ub9c9\uc740 \ub300\ubd80\ubd84\uc758 \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec\uc5d0\uc11c \ud575\uc2ec\uc801 \uc5ed\ud560\uc744 \ub2f4\ub2f9\ud55c\ub2e4. \uadfc\uac70\ub9ac \ubc0f \uc6d0\uac70\ub9ac \uc2e0\ud638 \uc804\ub2ec: \uc138\ud3ec \uc0ac\uc774\uc5d0\uc11c \ud654\ud559\uc2e0\ud638\ub294 \uc9c1\uc811\uc801\uc778 \uc138\ud3ec\uc9c8\uc758 \uc5f0\uacb0(\uac04\uadf9\uc5f0\uc811 \ub610\ub294 \uc6d0\ud615\uc9c8 \uc5f0\ub77d\uc0ac)\uc774\ub098 \ub9c9 \ud45c\uba74 \ubd84\uc790\uc758 \uc811\ucd09\uc73c\ub85c \uad50\ud658\ub420 \uc218 \uc788\ub2e4. \ub3d9\ubb3c\uc758 \uadfc\uac70\ub9ac \uc2e0\ud638 \uc804\ub2ec\uc5d0\uc11c\ub294 \uc2e0\ud638 \uc138\ud3ec\uac00 \uc2e0\ud638 \ubd84\uc790\ub4e4\uc744 \uc138\ud3ec\uc678\uc6a9\uc561\uc73c\ub85c \ubd84\ube44\ud558\uace0, \uc774 \uad6d\uc18c \uc870\uc808\uc790(local regulator)\ub4e4\uc774 \uac00\uae4c\uc774\uc5d0 \uc788\ub294 \uc138\ud3ec\uc5d0 \uc601\ud5a5\uc744 \uc900\ub2e4. \uc0dd\uc7a5 \uc778\uc790 (growth factors)\ub294 \uc774\ub7ec\ud55c \uad6d\uc18c […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[52,81,44],"tags":[76,115,113,116,117,112,118,114],"class_list":["post-2455","post","type-post","status-publish","format-standard","hentry","category-52","category-81","category-44","tag-76","tag-115","tag-113","tag-116","tag-117","tag-112","tag-118","tag-114"],"aioseo_notices":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/posts\/2455","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/comments?post=2455"}],"version-history":[{"count":3,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/posts\/2455\/revisions"}],"predecessor-version":[{"id":2494,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/posts\/2455\/revisions\/2494"}],"wp:attachment":[{"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/media?parent=2455"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/categories?post=2455"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/simagebank.net\/wp\/wp-json\/wp\/v2\/tags?post=2455"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}