추천 논문

제목Innate and adaptive immunity: specificities and signaling hierarchies revisited2023-09-15 20:27
작성자 Level 8

Innate and adaptive immunity: specificities and signaling hierarchies revisited

https://www.nature.com/articles/ni1153


Abstract

The conventional classification of known immune responses by specificity may need re-evaluation. The immune system can be classified into two subsystems: the innate and adaptive immune systems. In general, innate immunity is considered a nonspecific response, whereas the adaptive immune system is thought of as being very specific. In addition, the antigen receptors of the adaptive immune response are commonly viewed as 'master sensors' whose engagement dictates lymphocyte function. Here we propose that these ideas do not genuinely reflect the organization of immune responses and that they bias our view of immunity as well as our teaching of immunology. Indeed, the level of specificity and mode of signaling integration used by the main cellular participants in the adaptive and innate immune systems are more similar than previously appreciated.

댓글
자동등록방지
(자동등록방지 숫자를 입력해 주세요)
이전An introduction to immunology and immunopathology Level 82023-09-15
다음How Cells Coordinate Growth and Division Level 82023-09-15
Powered by MangBoard

Antibody, Microbiome, Mitochondria, Nanobodies, Protein engineering, Identification of Bacteria, Systems Biology, Structural biology,

Nanobodies

A comprehensive comparison between camelid nanobodies and single chain variable fragments

https://biomarkerres.biomedcentral.com/articles/10.1186/s40364-021-00332-6

The Therapeutic Potential of Nanobodies

https://link.springer.com/article/10.1007/s40259-019-00392-z

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

https://www.nature.com/articles/s41467-021-25480-z

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

https://www.science.org/doi/10.1126/science.abe3255

Antibody

Antibodies to combat viral infections: development strategies and progress

https://www.nature.com/articles/s41573-022-00495-3

Microbiome

Gut microbiota in human metabolic health and disease

https://www.nature.com/articles/s41579-020-0433-9

Current understanding of the human microbiome

https://www.nature.com/articles/nm.4517

A framework for microbiome science in public health

https://www.nature.com/articles/s41591-021-01258-0

Mitochondria

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

https://www.nature.com/articles/s41586-022-05288-7

Protein engineering

Advances in protein structure prediction and design

https://www.nature.com/articles/s41580-019-0163-x

https://www.nature.com/subjects/protein-engineering

Identification of Bacteria

16S rRNA 유전자 염기서열분석을 통한 임상 미생물학에서의 세균동정

https://kosen.kr/info/kosen/273696

16S rRNA 및 Internal Transcribed Spacer 염기서열 분석법을 이용한 세균 및 진균 동정

https://synapse.koreamed.org/upload/synapsedata/pdfdata/0105kjcm/kjcm-13-34.pdf