추천 논문 - SIMAGEBANK


제목	Long walk to genomics: History and current approaches to genome sequencing and assembly2023-09-11 12:33
작성자	simagebank
Long walk to genomics: History and current approaches to genome sequencing and assembly https://www.sciencedirect.com/science/article/pii/S2001037019303277 Abstract Genomes represent the starting point of genetic studies. Since the discovery of DNA structure, scientists have devoted great efforts to determine their sequence in an exact way. In this review we provide a comprehensive historical background of the improvements in DNA sequencing technologies that have accompanied the major milestones in genome sequencing and assembly, ranging from early sequencing methods to Next-Generation Sequencing platforms. We then focus on the advantages and challenges of the current technologies and approaches, collectively known as Third Generation Sequencing. As these technical advancements have been accompanied by progress in analytical methods, we also review the bioinformatic tools currently employed in de novo genome assembly, as well as some applications of Third Generation Sequencing technologies and high-quality reference genomes.

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이전	Cultivating DNA Sequencing Technology After the Human Genome Project	simagebank	2023-09-11
다음	DNA sequencing: an overview of solid-state and biological nanopore-based methods	simagebank	2023-09-11

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